中文字幕永久免费观看-蜜桃视频周晓琳一区二区-见贤思齐是什么意思-精品国产夫妻多人

客戶咨詢熱線:
Technical articles技術(shù)文章
首頁(yè) > 技術(shù)文章 >微波解決了蛋白質(zhì)研究的極限

微波解決了蛋白質(zhì)研究的極限

 更新時(shí)間:2012-11-16 點(diǎn)擊量:1922

        one of the greatest advances in solid phase peptide synthesis (SPPS) and proreomics over the past decade is the lise of microwave irradiation to overcome incomplete and slow reactions typical of conventional SPPS and  prorcomic sample preparation.

        Microwave energy has beell applied SlICcessfully in both manual and automated
approaches for enhancing the synthesis of pepridcs and peptidomimctics.

       During the course of conventional pcptide synthesis, the growing peptide chain can form aggregates with itself or neighboring chains, leading to the production of low-quality pcptides. Due to its highly charged resonance structure, the peptide bond will readily absorb microwave energy, which induces molecular morion within the peptide. This random morion can overcome chain aggregation within the peptide, allowing for free access to the N-terminus of the growing peptide chain and resulting in a significant increase in peptide purity.

        Microwave irradiation also call COllsiderably increase the speed at which peptides arc synrhesized. Traditionally, peptide coupling reactions require from 30 minutes up to two hours to reach completion. Microwave energy allows the amino acid coupling to be completed
in just five minutes.

        The Fmoc deprotection reaction can be accelerated in the microwave to decrease
the reaction time from at least 15 minutes to only three minutes. We recendy demonstrated
U. Pept. Sci., 2007) that common side reactions such as racemization and aspartimide formation are easily controllable with optimized methods that can be applied routinely.


 

更多詳情,請(qǐng)培安公司:
:北京: 上海:  成都: 廣州:
: sales@pynnco.comwww.pynnco.com
炉霍县| 云龙县| 沐川县| 孟连| 平邑县| 凉城县| 临城县| 乌鲁木齐县| 神池县| 肇东市| 大悟县| 建平县| 堆龙德庆县| 诏安县| 平江县| 镇江市| 林周县| 阳山县| 怀化市| 许昌县| 博爱县| 盐边县| 孝感市| 天柱县| 随州市| 夏津县| 溧阳市| 旬邑县| 通城县| 卢湾区| 衡阳市| 淮滨县| 株洲县| 昌平区| 上虞市| 格尔木市| 桦甸市| 阿拉善右旗| 松桃| 桑日县| 保靖县|