中文字幕永久免费观看-蜜桃视频周晓琳一区二区-见贤思齐是什么意思-精品国产夫妻多人

客戶咨詢熱線:
Technical articles技術(shù)文章
首頁 > 技術(shù)文章 >CEM微波合成用于Aspartimide的研究

CEM微波合成用于Aspartimide的研究

 更新時(shí)間:2012-06-29 點(diǎn)擊量:1742

INTRODUCTION

VIP (vasoactive intestinal peptide), a peptide hormone, has been implicated in a number of  biological processes including: increasing digestive system motility, stimulating pepsinogen  secretion, controlling the mammalian circadian timekeeping machinery, regulating prolactin secretion, and causing vasodilation. One problem with synthesis of VIP is aspartimide formation during Fmoc deprotection. Aspartimide formation occurs most frequently in peptides containing Asp followed by Asn(Trt), Gly, Thr, or Ser. The use of 5% piperazine with 0.1 M HOBt for the deprotection solution can readily reduce the amount of aspartimide formation during microwave peptide synthesis providing the VIP peptide in high crude purity compared to the conventional method.

Figure 1: Aspartimide Formation

 
 Liberty 全自動(dòng)流動(dòng)微波多肽合成系統(tǒng)
 
 
 

更多詳情,請(qǐng)培安公司:
:北京: 上海:  成都: 廣州:
: sales@pynnco.com  www.pynnco.com
祁东县| 西畴县| 永福县| 湘乡市| 龙江县| 甘泉县| 扶余县| 南靖县| 墨脱县| 平昌县| 西安市| 江西省| 武清区| 宁陕县| 昌乐县| 乌拉特前旗| 遂平县| 千阳县| 岢岚县| 安平县| 苏尼特左旗| 襄樊市| 晋宁县| 延庆县| 青浦区| 苍南县| 新营市| 高要市| 讷河市| 永城市| 井研县| 孟津县| 当涂县| 洛南县| 乾安县| 左贡县| 遂昌县| 平潭县| 博客| 左贡县| 南宫市|